Detyrosylation 

tyrosine can be removed by a carboxypeptidase, where it sequentially removes the C-terminal tyrosines from α-tubulin subunits. 

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#Unit 2. Cellular Organization

In yeast Rab protein is the Sec4 and its effectors are exocyst and Type V Myosin.

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#Unit 2. Cellular Organization

In mammalian cells, Rab5 protein (early endosomes) and its effector protein known as EEA1 (early endosome antigen 1)

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#Unit 2. Cellular Organization

Effector proteins of Rab6 is Kinesin

Effector proteins of Rab27 is Type V Myosin

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#Unit 2. Cellular Organization

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#Unit 2. Cellular Organization

Sets of SNARE Proteins responsible for the eventual fusion of a vesicle with the target membrane:

Vesicle-specific membrane protein, v-SNARE

Target membrane contains t-SNARE

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#Unit 2. Cellular Organization

SNARE-mediated fusion occurs during exocytosis of secreted proteins. In this case, 

v-SNARE, are VAMP 

t-SNAREs are syntaxin & SNAP-25