In smooth muscle, desmin filaments link cytoplasmic dense bodies to the plasma membrane to ensure that cells resist overstretching.

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#Id: 597

#Unit 2. Cellular Organization

Activator cII, Controls the Decision between Lytic and Lysogenic Growth upon Infection of a New Host

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#Id: 598

#Unit 2. Cellular Organization

Like the Lambda repressor, the cII protein is a transcriptional activator. It binds to a site upstream of a promoter called PRE (for repressor establishment) and stimulates transcription of the cI (repressor) gene from that promoter.

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#Id: 599

#Unit 2. Cellular Organization

The cI gene is transcribed from PRE when establishing lysogeny and from PRM when maintaining that state. 

PR controls not only lytic genes, but also expression of cII and is thus important in lysogeny as well as lytic development. PL which controls many lytic genes, also controls the cIII gene which helps establish lysogeny

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#Id: 600

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 601

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 602

#Unit 2. Cellular Organization

CII is a very unstable protein in E. coli; it is degraded by a specific protease called FtsH (HflB), encoded by the hfl gene.