Lamins 

contribute to genome organization as well as to the rigidity of the nucleus through linkages to the

cytoskeleton involving proteins with SUN and KASH domains

TLS Online TPP Program

#Id: 604

#Unit 2. Cellular Organization

The N gene codes for an antitermination factor whose action at nut (N utilization) sites allows transcription to proceed into the delayed early genes

 

TLS Online TPP Program

#Id: 605

#Unit 2. Cellular Organization

N protein prevents termination in the early operons of lambda and it works together with the products of the bacterial genes nusA, nusB, nusE, and nusG.

TLS Online TPP Program

#Id: 606

#Unit 2. Cellular Organization

N binds to RNA transcribed from DNA containing a nut sequence. Thus, once RNA polymerase has passed a nut site, N binds to the RNA and from there is loaded on to the polymerase itself. In this state, the polymerase is resistant to the terminators found just beyond the N and cro genes. 

TLS Online TPP Program

#Id: 607

#Unit 2. Cellular Organization

The E. coli trp operon contains the 5 genes Trp-EDCBA for the anabolic enzymes to make the tryptophan.

TLS Online TPP Program

#Id: 608

#Unit 2. Cellular Organization

Major enzyme is Tryptophan Synthase

TLS Online TPP Program

#Id: 609

#Unit 2. Cellular Organization

Major enzyme is Tryptophan Synthase whose activity is reduced when trp concentration is high.