Chk1, Chk2, and MK2

cause cell cycle arrest by inhibiting Cdc25

stabilizing the transcription factor p53, which induces the transcription of CKI p21 

TLS Online TPP Program

#Id: 7798

#Unit 2. Cellular Organization

Exportin-t

functions to export tRNAs & binds fully processed tRNAs in a complex with Ran⋅GTP

TLS Online TPP Program

#Id: 710

#Unit 3. Fundamental Processes

Deletion of dat causes initiation to occur more frequently. This significantly increases the amount of DnaA available to the origin

TLS Online TPP Program

#Id: 8870

#Unit 2. Cellular Organization

Fission yeast cells carrying a CDK1 mutation in which the tyrosine-15 residue is replaced by phenylalanine

show the same premature mitotic CDK activation and entry into mitosis.

TLS Online TPP Program

#Id: 7452

#Unit 5. Developmental Biology

ACG act as an osmosensor, so spores formed from the acg- cells will germinate irrespective of the osmotic conditions.

TLS Online TPP Program

#Id: 9092

#Unit 4. Cell Communication and Cell Signaling

Pertussis toxin, produced by Bordetella pertussis, catalyzes ADP-ribosylation of the  subunit of Gαi, preventing GDP-GTP exchange and blocking inhibition of adenylyl cyclase.