Ectoparasite A parasite that lives on the outside of an organism.

Endoparasite A parasite that lives inside an organism.

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

The heavy chain is then expressed on the cell surface in combination with the surrogate light chain, which is made up of VpreB and λ5. 

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

B- cell maturation

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

T1 and T2 Transitional B Cells

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

T1 cells are mIgMhi, mIgD -/lo, CD21-, CD23-, CD24+, and CD93+. 

T2 cells differ from T1 cells in having higher levels of mIgD and in expressing CD21 and CD23. 

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Transitional B cells bound for a follicular fate undergo positive and negative selection in the spleen.

TLS Online TPP Program

#Id: 10348

#Unit 4. Cell Communication and Cell Signaling

BAFF-R expression is first detected in T1 B cells and increases steadily there after.

Signaling through the BAFF/BAFF-R axis promotes survival of transitional B cells by inducing the synthesis of anti-apoptotic factors such as Bcl-2, Bcl-xl, and Mcl-1