The niche employs a variety of mechanisms of cell-to-cell communication to regulate the quiescent, proliferative, and differentiative states of the resident stem cell.

TLS Online TPP Program

#Id: 6703

#Unit 3. Fundamental Processes

Splicing of pre-tRNAs is catalyzed by proteins, not by RNAs. The box H/ACA snoRNPs are involved in pseudouridylylation, and box C/D snoRNPs function in 2-O-methylations

TLS Online TPP Program

#Id: 9615

#Unit 4. Cell Communication and Cell Signaling

Four related EGF receptors participate in signaling by the many members of EGF family :

In the mouse - Erb-B1, 2, 3, and 4

In humans - HER 1, 2, 3, and 4

TLS Online TPP Program

#Id: 177

#Unit 5. Developmental Biology

In Permissive interaction

The responding tissue has already been specified and needs only an environment that allows the expression of these traits. 

TLS Online TPP Program

#Id: 9458

#Unit 4. Cell Communication and Cell Signaling

JAK kinases become activated after ligand binding and

receptor dimerization

TLS Online TPP Program

#Id: 180

#Unit 5. Developmental Biology

Regional specificity of induction:

mesenchyme plays an instructive role, calling into play different sets of genes in the responding epithelial cells.