The prodomains of TGF-β1 and TGF-β3 contain a RGD motif, that allows them to bind to integrins.

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#Id: 7256

#Unit 5. Developmental Biology

B-10 B cells release the interleukin IL-10 upon antigenic stimulation, and may serve to reduce inflammation during an ongoing immune response.

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#Id: 7361

#Unit 5. Developmental Biology

On the left side of Hensen’s node, Sonic hedgehog (Shh) activates Cerberus, which stimulates BMPs to induce the expression of Nodal

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#Id: 7362

#Unit 5. Developmental Biology

In the presence of Nodal, the Pitx2 gene is activated

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#Id: 7363

#Unit 5. Developmental Biology

On the right side of the embryo, activin is expressed, along with activin receptor IIa. This activates Fgf8, a protein that blocks expression of the gene for Cerberus.

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#Id: 7364

#Unit 5. Developmental Biology

In the absence of Cerberus, Nodal is not activated and thus Pitx2 is not expressed

TLS Online TPP Program

#Id: 7365

#Unit 5. Developmental Biology

Drosophila eggs undergo Superficial cleavage.