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BMP proteins, activate a different set of receptors that are similar to the TGF-β RI and RII proteins but phosphorylate other R-Smads, Smad1, Smad5, & Smad8

#Unit 4. Cell Communication and Cell Signaling #TGF-β Signaling #Part B Pointers
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TLS Online TPP Program

#Id: 180

#Unit 5. Developmental Biology

Regional specificity of induction:
mesenchyme plays an instructive role, calling into play different sets of genes in the responding epithelial cells.

TLS Online TPP Program

#Id: 181

#Unit 5. Developmental Biology

Genetic specificity of induction:
mesenchyme may instruct the epithelium as to what sets of genes to activate, the responding epithelium can comply with these instructions only so far as its genome permits.

TLS Online TPP Program

#Id: 182

#Unit 5. Developmental Biology

Epithelial-Mesenchymal Transition
An orderly series of events whereby epithelial cells are transformed into mesenchymal cells.

TLS Online TPP Program

#Id: 183

#Unit 5. Developmental Biology

Morphogen is a diffusable biochemical molecule that can determine the fate of a cell by its concentration.


TLS Online TPP Program

#Id: 184

#Unit 5. Developmental Biology

Morphogens can be:
Transcription factors
Paracrine factors

TLS Online TPP Program

#Id: 185

#Unit 5. Developmental Biology

A morphogen specifies cells in a quantitative (“more or less”) manner.


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