The GAP for RAS (called a RAS-GAP) works by inserting one of its arginine side chains into the Ras active site, thus stabilizing an intermediate in the

hydrolysis reaction.

TLS Online TPP Program

#Id: 4617

#Unit 13. Methods in Biology

 Scatchard plots are based on repeated equilibrium dialyses with a constant concentration of antibody and varying concentration of ligand. 
If all antibodies have the same affinity, then a Scatchard plot yields a straight line with a slope of Ka. The x intercept is n, the valency of the antibody, which is 2 for IgG and other divalent Igs. For IgM, which is pentameric, n  10, and for dimeric IgA, n  4. In this graph, antibody #1 has a higher affinity than antibody #2.

TLS Online TPP Program

#Id: 728

#Unit 3. Fundamental Processes

DnaA is an ATP-binding protein and its binding to DNA is affected depending on whether ATP

TLS Online TPP Program

#Id: 8399

#Unit 2. Cellular Organization

The structure of the sarcomere is maintained by a number of accessory proteins: 

1. CapZ 

2.Tropomodulin

3.Titin 

4.Nebulin

TLS Online TPP Program

#Id: 10433

#Unit 4. Cell Communication and Cell Signaling

Carcinogens can be classified into two categories: 

1. Direct-acting carcinogens

2. Indirect-acting carcinogens

TLS Online TPP Program

#Id: 6459

#Unit 3. Fundamental Processes