Runaway selection: Females choose mates without the offering of obvious material benefits or parenting skills, and instead make their choices based on plumage color or courtship peahen may choose her peacock with long tail feather.

TLS Online TPP Program

#Id: 1423

#Unit 4. Cell Communication and Cell Signaling

The binding of integrins to their ligands depends on extracellular divalent cations(Ca+2 & Mg+2).

TLS Online TPP Program

#Id: 1424

#Unit 4. Cell Communication and Cell Signaling

The α subunit of each integrin is the primary determinant of its extracellular ligand specificity.

TLS Online TPP Program

#Id: 1425

#Unit 4. Cell Communication and Cell Signaling

Several integrin α subunits contain, I-domain, which can mediate binding of integrins to various collagens in the ECM.

TLS Online TPP Program

#Id: 1426

#Unit 4. Cell Communication and Cell Signaling

I-domains also recognize CAMs on other cells,  ICAMs, VCAMs and participate in cell-cell adhesion.

TLS Online TPP Program

#Id: 1427

#Unit 4. Cell Communication and Cell Signaling

The non-I-domain α subunits recognize RGD motif.

TLS Online TPP Program

#Id: 1428

#Unit 4. Cell Communication and Cell Signaling

TGF-β1 and TGF-β3 contain RGD motif that binds to integrins.