JAK kinases become activated after ligand binding and

receptor dimerization

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#Unit 7. System Physiology – Animal

The scala media, is continuous with the membranous labyrinth and does not communicate with the other two scalae

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#Unit 7. System Physiology – Animal

The basilar membrane is relatively permeable to perilymph in the scala tympani, and tunnel of the organ of Corti and the bases of the hair cells are bathed in perilymph

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#Unit 7. System Physiology – Animal

Auditory hair cells in the Organ of Corti are the sites of auditory transduction

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#Unit 7. System Physiology – Animal

The nerves that serve the organ of Corti are contained in the vestibulocochlear nerve (CN VIII)

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#Unit 7. System Physiology – Animal

The hair cells are arranged in four rows: 

Three rows of outer hair cells (20,000)

One row of inner hair cells (3500)

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#Unit 7. System Physiology – Animal

Covering the rows of hair cells is a thin, viscous, but elastic tectorial membrane in which the tips of the outer hair cells are embedded