Neutral theory of molecular evolution

Developed by Motoo Kimura, who argued that most of the evolution of DNA sequences occurs by chance (genetic drift) rather than by natural selection. 

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#Id: 9097

#Unit 4. Cell Communication and Cell Signaling

In response to elevated cytosolic Ca²+ 

PKC is recruited to the plasma membrane, where it is activated by DAG

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#Id: 344

#Unit 1. Molecules and their Interaction Relevant to Biology

The liver PK isozyme (L form) is regulated by glucagon

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#Id: 7157

#Unit 5. Developmental Biology

Gray Crescent 

The region opposite the point of sperm entry, where the greatest displacement of cytoplasm occurs (Gastrulation will begin)

Vegetal rotation: Vegetal cells asymmetrically press up against the inner blastocoel roof on the dorsal side.

Bottle cell formation and invagination: Localized apical constriction at the dorsal blastopore lip creates anisotropic forces that foster invagination.

Involution and cell migration: The leading edge of invaginating cells crawls up onto the blastocoel roof.

Convergence and extension: The targeted medial-to-lateral intercalation of cells on the midline (convergence) drives anterior-posterior axis elongation (extension).

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#Unit 13. Methods in Biology

The peptide or protein (known as a ‘ tag’) can be placed at the N- or C-terminal ends and provides a means for the fusion protein to be selectively purified from the cell extract by affinity chromatography.

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#Id: 1108

#Unit 2. Cellular Organization

E1’s ion-binding sites are exposed to the cytoplasm, and it has high affinity for Na+ but low affinity for K+