Phosphorylation causes the binding of AS160 to the 

14-3-3 protein that sequesters it in the cytosol away from its target Rab proteins

TLS Online TPP Program

#Id: 659

#Unit 3. Fundamental Processes

Telomeric sequence is the extension of the G-T–rich strand, which for 14 to 16 bases is usually a single strand.

TLS Online TPP Program

#Id: 660

#Unit 3. Fundamental Processes

G-tail is probably generated because there is a specific limited degradation of the C-A–rich strand.

TLS Online TPP Program

#Id: 661

#Unit 3. Fundamental Processes

Drosophila telomeres are an exception, consisting of terminal arrays of retrotransposons.

TLS Online TPP Program

#Id: 662

#Unit 3. Fundamental Processes

Telomeres cluster on the nuclear envelope just prior to homologous chromosome synapsis during meiosis.

TLS Online TPP Program

#Id: 663

#Unit 3. Fundamental Processes

Telomeric clustering on nuclear envelope called as the “bouquet” stage of meiosis, and represents a once-in-a-lifecycle configuration.

TLS Online TPP Program

#Id: 664

#Unit 3. Fundamental Processes

The meiotic telomere cluster is visualized by telomere fluorescent in situ hybridization (FISH). Microscopic image of a maize nucleus fixed at meiotic prophase (zygotene stage), subjected to telomere (green) and centromere (white) FISH, and counterstained for total DNA with DAPI (red).