IFN-ϒ acts directly by inducing an antiviral state in nearby cells.

IL-2 acts indirectly by assisting the development of cytotoxic T lymphocyte(CTL) precursors into an effector population.

Both IL-2 and IFN-ϒ activate NK cells.

TLS Online TPP Program

#Id: 441

#Unit 2. Cellular Organization

When spaced at about, consecutive AT base pair has 10 bp intervals as consecutive GC base pairs they are offset by 5 bp from runs of AT base pairs.

TLS Online TPP Program

#Id: 442

#Unit 2. Cellular Organization

The nucleosome have 200 bp of DNA with octameric basic proteins into a beadlike structure.

TLS Online TPP Program

#Id: 443

#Unit 2. Cellular Organization

Individual nucleosomes can be obtained by treating chromatin with the endonuclease micrococcal nuclease (MNase), which cuts the DNA at linker DNA.

TLS Online TPP Program

#Id: 444

#Unit 2. Cellular Organization

The high-mobility group (HMG) are nonhistones and may contain Transcriptional Factors.

TLS Online TPP Program

#Id: 445

#Unit 2. Cellular Organization

Core DNA has an invariant length of 146 bp, the minimum length of DNA needed to form a stable monomeric nucleosome, and is relatively resistant to digestion by nucleases- DNA FINGER PRINTING

TLS Online TPP Program

#Id: 446

#Unit 2. Cellular Organization

Linker DNA comprises the rest of the repeating unit. Its length varies from as little as 8 bp to as many as 114 bp per nucleosome.