What is a primary function of transcription factors?

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#Question id: 183

#Unit 1. Molecules and their Interaction Relevant to Biology

At pH 7.0, converting a glutamic acid to gamma-carboxyglutamate, will have what effect on the overall charge of the protein containing it?

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#Question id: 26430

#Unit 3. Fundamental Processes

If the mismatch is near 5’ then which of the following will degrade strands of DNA in the 3’ → 5’ direction

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#Question id: 3437

#Unit 11. Evolution and Behavior

Learning in which an associated stimulus may be used to elicit the same behavioral response as the original sign stimulus is called

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#Question id: 12485

#Unit 2. Cellular Organization

Following statements are regarding to the centrosome cycle of an animal cell.

A. During G1, the daughter procentrioles continue to elongate.

B. During S phase, daughter procentrioles form adjacent to maternal centrioles so that two pairs of centrioles become visible within the centrosome. 

C. During G2 phase, the centrosome contains a single pair of centrioles.

D. At the beginning of mitosis, the centrosome splits, with each pair of centrioles becoming part of its own centrosome. As they separate, the centrosomes organize the microtubule fibres that make up the mitotic spindle.

Which of the following option is correct? 

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#Question id: 15302

#Unit 5. Developmental Biology

FOXP1 is a transcription factor which stimulate the production of Oct4 and Nanog and establish pluripotency. Which of the following statements are correct regarding to the mechanism of alternative splicing of FOXP1. 

A. There are two isoforms of the FoxP1 protein, One is the product of an mRNA spliced to include a particular exon, 18b, while the other splicing variant carries exon 18a.

B. When alternative splicing generates a form including exon 18b in place of 18a, the resulting isoform (FOXP1-ES) binds to a different DNA sequence and thus controls expression of a different set of genes.

C. The protein encoded by the exon 18b– carrying mRNA is called FOXP1-ES it fails to stimulate expression of OCT4 and NANOG and instead actives genes that promote differentiation. 

D. The exon 18a– containing form encodes FOXP1 itself, and this has the opposite effect: this activates genes that promote dedifferentiation, and thus stimulates iPS cell formation.