Many G protein-coupled receptors contain seven transmembrane α-helical domains. The amino end of the protein lies at the exterior of the plasma membrane. Loops of amino acids connect the helices either at the exterior surface or on the cytosolic surface of the membrane. The loop on the cytosolic side between helices 5 and 6 is usually substantially longer than the others. Where would you expect to find the carboxyl end of the protein?

#Question id: 4405

#Unit 3. Fundamental Processes

Which of the following can occur when steroid hormone binds to its cognate receptor?

a. conformational changes in the receptor

b. translocation of the receptor out of the cell membrane

c. binding of the receptor to DNA response elements

d. stimulation of transcription

#Question id: 4406

#Unit 3. Fundamental Processes

An electrophoretic mobility shift assay (EMSA) was conducted to check for the binding of TFIIB to a segment of a DNA promoter region. Which of the following approaches could be used to confirm that TFIIB is indeed binding?

#Question id: 4407

#Unit 3. Fundamental Processes

The general transcriptional factors are used by all sets of RNA Polymerase. Which of the following GTF is/are commonly used by all RNA Polymerases?

A. TBP

B. TFIID

C. TFIIIC

D.TFIIE

E. TFIIH

#Question id: 4408

#Unit 3. Fundamental Processes

an example/s of in vivo “molecular mimicry” is/are

I. EF-G–GDP and EF-Tu–GTP–tRNA

II. TAF42 -TAF62 and H3.H4 tetramer

III. Tyrosinyl-tRNA and Puromycin

#Question id: 4409

#Unit 3. Fundamental Processes

The torpedo model of termination is

A. Degradation of the second RNA as it emerges from the RNA polymerase

B. It Involves Rat1/Xrn2 to degrade and dislodge the RNA Polymerase

C. Inhibition of second replication cycle as Mitotic cdkc is freed

D. It Involves APC/C cdh1 to Mitotic cdkc

#Question id: 4410

#Unit 3. Fundamental Processes

A key component of the eukaryotic transcription machinery called TFIID includes a