TLS Online TPP Program

#Question id: 1222


Particular receptor tyrosine kinases (RTKs) that promote excessive cell division are found at high levels in various cancer cells. HER2 is an RTK that is present at excessively high levels in some breast cancer cells. Herceptin is a protein that binds to HER2 and inhibits cell division. Herceptin may be an effective treatment for breast cancer treatment under which of the following conditions?

#Unit 4. Cell Communication and Cell Signaling
  1. If injection of HER2 in the patient's cancer cells stimulates cell division.

  2. If the patient's cancer cells have excessive levels of HER2.

  3. If the patient's genome codes for the HER2.

  4. If the patient has excessive levels of other RTKs in cancer cells.

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TLS Online TPP Program

#Question id: 4792

#Unit 8. Inheritance Biology

A number of all-white cats are crossed and they produce the following types of progeny: 12/16 all-white, 3/16 black and 1/16 gray. If the genotype black progeny is A_bb. Which of the following statement are correct?

a. Epistatic genes is recessive.

b. Epistatic gene is dominant

c. A gene is dominant epistatic

d. B gene is dominant epistatic

e. aa gene is recessive epistatic

f. bb gene is recessive epistatic

TLS Online TPP Program

#Question id: 4793

#Unit 8. Inheritance Biology

Hypophosphatemia is caused by an X-linked dominant gene in humans. Normal man marries with Hypophosphatemia woman whose father is normal. What will be observation in their child is correct?

a. All daughters affected                                      b. half of their daughters affected

c. All sons affected                                              d. half of their son’s affected

TLS Online TPP Program

#Question id: 4794

#Unit 8. Inheritance Biology

 Following statement given for a character

A- Characteristics are determined by autosomal genes

B- Inherited according to Mendel’s principles

C-they are different expressivity in males and females

Which of the following having above statements feature?

TLS Online TPP Program

#Question id: 4795

#Unit 8. Inheritance Biology

 There is Gene A is normal growth while mutant allele a was shown to small size. A allele dominant over a allele.

Condition

Male Parent genotype

Female parent genotype

Offspring Phenotype

Maternal imprinting

AA

aa

i

Paternal Imprinting

AA

aa

ii

Genetic Maternal effect

AA

aa

iii

No Genomic Imprinting

AA

aa

iv


TLS Online TPP Program

#Question id: 4796

#Unit 8. Inheritance Biology

Trait is encoded by  genes that are expressed in only one sex . In domestic chickens, display a feather pattern in male and female

Genotype                        Male phenotype           Female phenotype

HH                             hen feathering                      hen feathering

Hh                         hen feathering                            hen feathering

hh             cock feathering (plumage pattern )         hen feathering

If cross between Hh and Hh. what is probability of their progeny with cock feathering

TLS Online TPP Program

#Question id: 4797

#Unit 8. Inheritance Biology

Non allelic genotype aa governing white phenotype with recessive epistatic over non allelic gene B for red phenotype Which of the following cross would produce 25 % white phenotype in their offspring?