Place the events that follow the binding of a ligand to a G protein-coupled receptor that acts on adenylyl cyclase in the correct order:

a. GTP is hydrolyzed to GDP.           

b. GDP is displaced from Gα.           

c. the Gα-GTP complex dissociates from the Gβγcomplex.  

d. GTP is bound to Gα. 

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#Question id: 7128

#Unit 5. Developmental Biology

Imagine that in an attempt to get the â-globin gene to be expressed in B-cells, the transcription factors (GATA-1 and GATA-2) known to control the â-globin gene in erythrocytes were introduced into B-cells, yet the â-globin gene was not expressed. What is a likely explanation for this result?

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#Question id: 7129

#Unit 5. Developmental Biology

What is the developmental pathway by which the hematopoietic stem cell gives rise to a macrophage?

TLS Online TPP Program

#Question id: 7130

#Unit 5. Developmental Biology

Hematopoietic stem cells can be isolated and grown in culture; if one wished to control their differentiation into either neutrophils or macrophages, what colony stimulating factors could be used?

TLS Online TPP Program

#Question id: 7131

#Unit 5. Developmental Biology

What is globin gene switching?

TLS Online TPP Program

#Question id: 7132

#Unit 5. Developmental Biology

What happens if you introduce the gene myoD into fibroblast cells growing in culture?

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#Question id: 7133

#Unit 5. Developmental Biology

In what way are mrf4, myoD, and the other muscle-inducing genes similar to the homeotic genes of Drosophila?