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TLS Online TPP Program

#Question id: 1260

Which of the following statement regarding RTK/Ras pathway is incorrect?

#Unit 4. Cell Communication and Cell Signaling

  1. Receptor activation leads to re-localization of Sos from the cytosol to the membrane, which brings Sos close to its substrate, Ras∙GDP, which is already bound to the plasma membrane by means of a covalently attached lipid.

  2. Binding of Sos to Ras∙GDP leads to conformational changes in the switch I and switch II segments of Ras, thereby opening the binding pocket for GDP so it can diffuse out.

  3. The SH2 domains in GRB2 selectively bind to proline-rich sequences in Sos; different SH3 domains in other proteins bind to proline-rich sequences distinct from those in Sos.

  4. Ras is activated by the exchange of GDP for GTP. Active Ras∙GTP binds to the N-terminal regulatory domain of Raf, a serine/threonine kinase, thereby activating its kinase activity.

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TLS Online TPP Program

#Question id: 28420

#Unit 5. Developmental Biology

Which of the following cell is involved to shedding of most of the deep cells during chick development?
TLS Online TPP Program

#Question id: 11881

#General Aptitude

Three tankers contain 403 litres, 434 liters and 465 liters of diesel respectively. Then the maximum capacity of a container that can measure the diesel of the three containers the exact number of times is
TLS Online TPP Program

#Question id: 1588

#Unit 4. Cell Communication and Cell Signaling

A patient reports severe symptoms of watery, itchy eyes and sneezing after being given a flower bouquet as a birthday gift. A reasonable initial treatment would involve the use of
TLS Online TPP Program

#Question id: 11866

#General Aptitude

The product of two numbers is 216. If the HCF is 6, then their LCM is
TLS Online TPP Program

#Question id: 20713

#Unit 12. Applied Biology

Under anaerobic conditions and in the presence of what microbial electron transfer and respiration can proceed if suitable exogenous electron acceptors are available