Following statements are regarding to the formins which involve in filament assembly.

A. All formin family members have two adjacent domains in common, the so called FH1 and FH2 domains (formin-homology domains 1 and 2).

B. Two FH2 domains from two individual formin monomers associate to form a doughnut-shaped complex can form a dimer and nucleate filament assembly.

C. The FH1 domain of formin is rich in proline residues, which serve as sites for the binding of several profilin molecules.

D. The FH2 domain behaves as a landing site for profilin–ATP–G-actin to increase the local concentration of these complexes.

E. Formins are activated by membrane bound Rho-GTP, a Ras-related small GTPase.

Which of the following combination is correct?

#Question id: 463

#Unit 1. Molecules and their Interaction Relevant to Biology

Thioesters are similar to oxygen esters of carboxylic acids except that

#Question id: 464

#Unit 1. Molecules and their Interaction Relevant to Biology

Calculate the equilibrium constant for an oxidation-reduction reaction involving the transfer of 1 mole of electrons with DE0ʹ= 0.25 V. (R = 8.315 JK-1mol-1, F = 96.48 kJV-1mol-1, T = 298 K)

#Question id: 465

#Unit 1. Molecules and their Interaction Relevant to Biology

If the standard reduction potential of a certain half-reaction is -0.30 V, which statement below is true for this half-reaction to proceed as a reduction?

#Question id: 466

#Unit 1. Molecules and their Interaction Relevant to Biology

When a reduction half-reaction is ________ (negative, positive), electrons flow to the more readily reduced substance which is ________ (negative, positive) in value.

#Question id: 467

#Unit 1. Molecules and their Interaction Relevant to Biology

The standard potential for electron transfer can be related to the standard free-energy change for redox reactions by using

#Question id: 468

#Unit 1. Molecules and their Interaction Relevant to Biology

Glycolysis is the name given to a metabolic pathway occurring in many different cell types.  It consists of 11 enzymatic steps that convert glucose to lactic acid.  Glycolysis is an example of