#Question id: 3806
#Unit 3. Fundamental Processes
How are damaged nucleotides recognized by DNA repair enzymes?
#Question id: 3807
#Unit 3. Fundamental Processes
If the genes from the following list were damaged, which gene would most likely be repaired first?
#Question id: 3808
#Unit 3. Fundamental Processes
Fibroblast cells from several different xeroderma pigmentosa patients were cultured, then fused in intergenic complementation studies. Which cell fusions would not result in a hybrid capable of repairing damaged DNA?
#Question id: 3809
#Unit 3. Fundamental Processes
MMR is a highly conserved biological pathway. Several human MMR proteins have been identified based on their homology to E. coli MMR proteins. Match the following
|
Human |
Function |
|
1. MSH2-MSH6 |
A. DNA mismatch/damage recognition |
|
2. MLH-PMS |
B. Molecular matchmaker |
|
3. MutH |
C. Strand discrimination |
|
D. Absent in Human |
#Question id: 3810
#Unit 3. Fundamental Processes
In the diagram below, the dotted line marks the point of initiation of bidirectional replication
A. On the right side of the dotted line, leading strand synthesis occurs using the lower strand as the template.
B. On the right side of the dotted line, leading strand synthesis occurs using the upper strand as the template.
C. A ligase deficient (lig- ) mutant would affect replication of t11e upper strand on the left side of the dotted line.
D. A ligase deficient (lig- ) mutant would affect replication of the lower strand on the left side
of the dotted line_
Which one of the following options represents the combinations of the CORRECT statements?
#Question id: 3811
#Unit 3. Fundamental Processes
The mechanism of DNA replication is studied in an E. coli replication fork. Which is a characteristic of this replication fork?