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TLS Online TPP Program

#Question id: 1368

The following statements are made with reference to the characteristic of proteoglycans (major constituents of ECM). Which one of them is incorrect?

#Unit 4. Cell Communication and Cell Signaling

  1. Perlecan the major secreted proteoglycan in basal laminae, consists of a large multidomain core protein (∼470 kDa) to which polysaccharides are covalently attached.

  2. Perlecan contains three types of covalent polysaccharide chains: N-linked chains, O-linked chains, and glycosaminoglycans (GAGs).

  3. Perlecan can be found in basal laminae and in non–basal laminal ECM.

  4. The adhesion receptor dystroglycan can bind perlecan indirectly, via perlecan’s LG domains, and directly, via its binding to laminin.

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TLS Online TPP Program

#Question id: 32317

#Unit 2. Cellular Organization

What type of interaction occurs between the β-propeller domain and the LDL-binding domain at low pH?
TLS Online TPP Program

#Question id: 1910

#Unit 4. Cell Communication and Cell Signaling

Hyperacute graft rejection is caused by:
TLS Online TPP Program

#Question id: 15191

#Unit 8. Inheritance Biology

Genes that control coat color in mammals represent some of the best early examples of genes with multiple alleles exhibiting different phenotypes. A classic example is the C gene in hamsters. Three of the known alleles of this gene are C, ck and ca. Each supplies a different amount of black pigment to the coat hair. The phenotypes of three different homozygous strains are as follows.
Based on the concepts of dominance, determine whether ck and ca were dominant or recessive alleles by crossing the true-breeding sepia hamsters to true-breeding black hamsters. From the resulting F1 progeny phenotype, what would be the ratio of F2 phenotype
TLS Online TPP Program

#Question id: 27933

#Unit 11. Evolution and Behavior

The evolutionary change happening below the level of species
TLS Online TPP Program

#Question id: 660

#Unit 1. Molecules and their Interaction Relevant to Biology

Computers are used to advance the understanding of three dimensional protein structure by