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TLS Online TPP Program
#Question id: 12220
#Unit 7. System Physiology – Animal
A female patient has unexplained severe hypernatremia (plasma Na+ = 167 mmol/L) and complains of frequent urination and large urine volumes. A urine specimen reveals that the Na+ concentration is 15mmol/L (very low) and the osmolarity is 155 mOsm/L (very low). Laboratory tests reveal: plasma renin activity = 3 ng angiotensin I/ml/hr (normal = 1.0), plasma antidiuretic hormone (ADH) = 30 pg/ml (normal = 3 pg/ml), and plasma aldosterone = 20 ng/dL (normal = 6 ng/dL). Which of the following is the most likely reason for her hypernatremia?
TLS Online TPP Program
#Question id: 12221
#Unit 7. System Physiology – Animal
Juvenile (type I) diabetes mellitus is often diagnosed because of polyuria (high urine flow) and polydipsia (frequent drinking) that occur because of which of the following?
TLS Online TPP Program
#Question id: 12222
#Unit 7. System Physiology – Animal
In acidosis, most of the hydrogen ions secreted by the proximal tubule are associated with which of the following processes?
TLS Online TPP Program
#Question id: 12275
#Unit 7. System Physiology – Animal
Two weeks after constricting the renal artery of a sole remaining kidney to initially reduce renal artery pressure by 20 mm Hg (from 100 to 80 mm Hg), which of the following changes would you expect, compared with before constriction of the artery?
TLS Online TPP Program
#Question id: 12276
#Unit 7. System Physiology – Animal
Because the usual rate of phosphate filtration exceeds the transport maximum for phosphate reabsorption, which of the following is true?
TLS Online TPP Program
#Question id: 12300
#Unit 7. System Physiology – Animal
Which of the following changes, compared with normal, would be expected to occur, under steady-state conditions, in a patient whose severe renal disease has reduced the number of functional nephrons to 25% of normal?