TLS Online TPP Program

#Question id: 1447


A patient with B cell leukemia donates some cancer cells for analysis. The cells do not contain the usual chromosomal translocations associated with leukemia. Instead, a sporadic mutation seems to have arisen in a certain gene, followed by loss of heterozygosity in the second copy. This gene product is most likely:

#Unit 4. Cell Communication and Cell Signaling
  1. Ras.

  2. Rb.

  3. VEGF.

  4. telomerase.

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TLS Online TPP Program

#Question id: 12693

#Unit 8. Inheritance Biology

A panel of cell lines was created by human-mouse cell line hybridization. Each line was examined for the presence of  human chromosome and for the gene production. The following result were obtained;
On the basis of these results, which chromosome has the gene  that encodes the enzyme ?

TLS Online TPP Program

#Question id: 12694

#Unit 8. Inheritance Biology

A panel of cell lines was created by human—mouse somatic-cell hybridization. Each line was examined for the presence of human chromosomes and for the production of an enzyme. The following results were obtained: 

On the basis of these results, which chromosome has the gene that encodes the enzyme? 

TLS Online TPP Program

#Question id: 12695

#Unit 8. Inheritance Biology

A panel of cell lines was created by human—mouse somatic-cell hybridization. Each cell line was examined for the presence of human chromosomes and for the production of three enzymes. The following results were obtained: 

On the basis of these results, give the chromosomal locations of the genes encoding enzyme 1, enzyme 2, and enzyme 3. 

TLS Online TPP Program

#Question id: 12696

#Unit 8. Inheritance Biology

The following is a schematic representation of region of the chromosome of fly along with extent of six deletions (Del 1 to Del 6); 
When flies homozygous for the recessive mutations are crossed with flies heterozygous for the deletions, the following results are obtained, in which "m" represents a mutant phenotype and a plus sign (+) represents the wild type. On the basis of these data, determine the relative order of the seven mutant eenes on the chromosome. 

TLS Online TPP Program

#Question id: 12707

#Unit 8. Inheritance Biology

AaBb=100% chance of crossing over between gene A and B than chance of  recombination?

TLS Online TPP Program

#Question id: 12708

#Unit 8. Inheritance Biology

800 meiocytes with the genotype AaBb undergoes meiosis with 60% chance of crossing over with A and B. How many recombinant gamete form?