TLS Online TPP Program

#Question id: 1448


Cancer genome analysis has been utilized for all the following applications, except:

#Unit 4. Cell Communication and Cell Signaling
  1. to identify which patients are good candidates for molecularly targeted drugs.

  2. to identify cancerous cells in a biopsy based on morphological characteristics.

  3. to identify driver mutations.

  4. to identify the link between chromothripsis and aggressive neuroblastoma.

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TLS Online TPP Program

#Question id: 31227

#Unit 2. Cellular Organization

Fission yeast cells carrying a CDK1 mutation in which the tyrosine-15 residue is replaced by phenylalanine, what will be the result?
a) Shows larger than normal cells
b) Shows smaller than normal cells
c) allows the phosphorylation of phenylalanine and normal cell proliferation are seen
d) premature mitotic CDK activation and entry into mitosis

TLS Online TPP Program

#Question id: 11286

#Unit 10. Ecological Principles

Consumption, assimilation, and production efficiencies are measures of ecological efficiency. Following some statements are correct?

(A) Consumption efficiencies for carnivores are typically higher than those of herbivores

(B) Assimilation efficiencies of herbivore are often less than consumption efficiencies

(C) Vertebrates tend to have lower production efficiencies than invertebrates

TLS Online TPP Program

#Question id: 34088

#Unit 3. Fundamental Processes

How can the 2D gels identify the DNA intermediates associated with a replication origin? Choose combination of correct statements

A. Y-shaped molecule that has three equal length arms will migrate the most slowly of all such molecules derived from a particular DNA fragment
B. A Y-shaped molecule with two very short replicated arms and a large replicated region will migrate very similarly to the unreplicated version of the same DNA fragment. 
C. Y-shaped molecule that results from the almost completely replicated fragment is similar in shape to a linear molecule two times the size of the unreplicated fragment.

TLS Online TPP Program

#Question id: 4519

#Unit 3. Fundamental Processes

Some steroid hormone receptors function in the nucleus as transcription activators, stimulating the transcription of certain genes when a particular steroid hormone signal is present. When the hormone is absent, the receptor proteins revert to a repressor conformation, preventing the formation of PICs. It is an example of;

TLS Online TPP Program

#Question id: 28676

#Unit 2. Cellular Organization

Which of the following protein is responsible for the formation of the mitotic spindle as well as for chromosome segregation?