Fever is an abnormal elevation of body temperature. Following statements are regarding to the cellular mechanism of fever.

A. Pyrogens produce fever by increasing the hypothalamic set-point temperature.

B. the mechanism of pyrogen action is increased production of interleukin-1 (IL-1) in phagocytic cells.

C. IL-1 then acts on the anterior hypothalamus to increase local production of prostaglandins, which increase the set-point temperature.

D. IL-1 then acts on the posterior hypothalamus to increase local production of prostaglandins, which increase the set-point temperature.

E. IL-1 then acts on the posterior hypothalamus to increase local production of prostaglandins, which decrease the set-point temperature.

Which of the following combination is correct?

#Question id: 4339

#Unit 3. Fundamental Processes

In positive control of several sugar metabolism-related operons, the cAMP receptor protein (CRP) binds to DNA to stimulate transcription. Which of the following environmental conditions causes an increase in CRP activity in stimulating transcription?

#Question id: 4340

#Unit 3. Fundamental Processes

There is a mutation that is found in E. coli in the repressor that results in a molecule known as a super-repressor because it represses the lac operon permanently. Which of the following characteristics would you expect to observe in such a mutant?

#Question id: 4341

#Unit 3. Fundamental Processes

Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. If a researcher moves the promoter for the lac operon to the region between the beta galactosidase (lacZ) gene and the permease (lacY) gene, which of the following results would be most likely?

#Question id: 4342

#Unit 3. Fundamental Processes

Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. If a researcher moves the operator to the far end of the operon, past the transacetylase (lacA) gene, which of the following processes would likely occur when the cell is exposed to lactose?

#Question id: 4343

#Unit 3. Fundamental Processes

Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. If a researcher moves the repressor gene (lacI), along with its promoter, to a position at some several thousand base pairs away from its normal position, which of the following results would be expected?

#Question id: 4344

#Unit 3. Fundamental Processes

How does the transcription of structural genes in an inducible operon occur?