Practice Questions

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#Question id: 16140

Many mouse genes are “tissue-specific,” that is, they are present throughout the body but are expressed in only one of the animal’s many tissue types. (Other mouse genes are expressed throughout the body, or in multiple tissues.) Geneticists can study the regulation of a mouse gene by fusing the gene’s promoter region to the LacZ coding sequence and injecting the construct to create a transgenic mouse. Fusion of the mouse amylase promoter to LacZ yielded a Pamylase-LacZ construct.
You are surprised to observe that mice homozygous for the transgene insertion display a serious heart defect. (Heterozygotes have normal hearts.) which one is a possible explanation?
a) LacZ overexpression (with two copies of the transgene) causes the defect.
b) the insertion disrupted a gene that is haploinsufficient.
c) the insertion disrupted a gene that is haplosufficient.
d) LacZ expression inhibition (with two copies of the transgene) causes the defect.
Which of the following statements is correct predict about the heart defect?

#Unit 13. Methods in Biology

A and C
C and D
A and B
B and D

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#Question id: 3632

#Unit 8. Inheritance Biology

geneticist is working with a new bacteriophage called phage Y3 that infects E. coli. He has isolated eight mutant phages that fail to produce plaques when grown on E. coli strain K. To determine whether these mutations occur at the same functional gene, he simultaneously infects E. coli K cells with paired combinations of the mutants and looks to see whether plaques are formed. He obtains the following results. (A plussign means that plaques were formed on E. coli K; a minussign means that no plaques were formed on E. coli K.)

How many cistron belong to these mutation?

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#Question id: 1904

#Unit 4. Cell Communication and Cell Signaling

What is the target of the monoclonal antibody basiliximab used to help suppress allograft rejection?

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#Question id: 32436

#Unit 2. Cellular Organization

In microtubules, the end with exposed β-subunits is the ___?___, while the end with exposed α-subunits is the __?____.

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#Question id: 16485

#Unit 12. Applied Biology