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TLS Online TPP Program

#Question id: 16140

Many mouse genes are “tissue-specific,” that is, they are present throughout the body but are expressed in only one of the animal’s many tissue types. (Other mouse genes are expressed throughout the body, or in multiple tissues.) Geneticists can study the regulation of a mouse gene by fusing the gene’s promoter region to the LacZ coding sequence and injecting the construct to create a transgenic mouse. Fusion of the mouse amylase promoter to LacZ yielded a Pamylase-LacZ construct.
You are surprised to observe that mice homozygous for the transgene insertion display a serious heart defect. (Heterozygotes have normal hearts.) which one is a  possible explanation?
a) LacZ overexpression (with two copies of the transgene) causes the defect.
b) the insertion disrupted a gene that is haploinsufficient.
c) the insertion disrupted a gene that is haplosufficient.
d) LacZ expression inhibition (with two copies of the transgene) causes the defect.
Which of the following statements is correct  predict about the  heart defect?

#Unit 14. Methods in Biology
  1. A and C
  2. C and D
  3. A and B
  4. B and D
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TLS Online TPP Program

#Question id: 21243

#Unit 7. System Physiology – Animal

A 62-year-old Caucasian woman experienced a rapid onset of blurry vision along with loss of central vision. A comprehensive eye exam showed that she had wet age-related macular degeneration. The fovea of the eye
TLS Online TPP Program

#Question id: 21244

#Unit 7. System Physiology – Animal

Which of the following parts of the eye has the greatest concentration of rods?
TLS Online TPP Program

#Question id: 21245

#Unit 7. System Physiology – Animal

Which of the following is not correctly paired?
TLS Online TPP Program

#Question id: 21246

#Unit 7. System Physiology – Animal

The correct sequence of events involved in phototransduction in rods and cones in response to light is:
TLS Online TPP Program

#Question id: 21247

#Unit 7. System Physiology – Animal

A 25-year-old medical student spent a summer volunteering in the sub-Saharan region of Africa. There he noted a high incidence of people reporting difficulty with night vision due to a lack of vitamin A in their diet. Vitamin A is a precursor for the synthesis of
TLS Online TPP Program

#Question id: 21248

#Unit 7. System Physiology – Animal

An 11-year-old male was having difficulty reading the graphs that his teacher was showing at the front of classroom. His teacher recommended he be seen by an ophthalmologist. Not only was he asked to look at a Snellen letter chart for visual acuity but he was also asked to identify numbers in an Ishihara chart. He responded that he merely saw a bunch of dots. Abnormal color vision is 20 times more  common in men than women because most cases are caused by an abnormal