TLS Online TPP Program

#Question id: 1508


Of the following statements explaining how alterations of the ras gene cause cancer, which is true?

#Unit 4. Cell Communication and Cell Signaling
  1. A base substitution in the c-ras gene that replaces a critical glycine with another amino acid.

  2. Infection of the cell by a tumor virus carrying a v-ras gene.

  3. Linkage of the c-ras gene to a viral promoter.

  4. All of the above statements are true.

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TLS Online TPP Program

#Question id: 4503

#Unit 3. Fundamental Processes

Pol I transcribes the human rRNA genes, the promoter for the rRNA gene comprises two parts: the core element and the UCE (upstream control element), for initiation there are two factors-

TLS Online TPP Program

#Question id: 4504

#Unit 3. Fundamental Processes

What will be the molecular weight of poly(A) chain consisting of 100 residues, where weight of AMP is 500?

TLS Online TPP Program

#Question id: 4505

#Unit 3. Fundamental Processes

Symplekin protein is participats in which of the following processes;

TLS Online TPP Program

#Question id: 4506

#Unit 3. Fundamental Processes

Which process is very much similar to polyadenylation, because its takes place by the multiple protein complexes,

TLS Online TPP Program

#Question id: 4507

#Unit 3. Fundamental Processes

A group of introns that-unlike those we have considered thus far-can splice themselves out of pre-mRNA without the need for the spliceosome, they are called

TLS Online TPP Program

#Question id: 4508

#Unit 3. Fundamental Processes

Statement: In the case of group II introns, the chemistry of splicing and the RNA intermediates produced are the same as those for nuclear pre-mRNA.

 Explanations: I. The intron uses an A residue within the branch site to attack the phosphodiester bond at the boundary between its 5’ end and the end of the 5’ exon-that is, at the 5’ splice site. This reaction produces the branched lariat.

II. A second reaction in which the newly freed 3’ -OH of the exon attacks the 3’splice site, releasing the intron as a lariat and fusing the 3’ and 5’ exons.