TLS Online TPP Program

#Question id: 1512


There is evidence that the accumulation of abnormal or damaged proteins due to impairment of the pathway contributes to a number of neurodegenerative diseases, including Alzheimer’s. In contrast, deliberately blocking the pathway in cancer cells could lead to a disruption of protein regulation that in turn could cause the apoptosis of the malignant cells. Accordingly, proteasome inhibitors have been developed for evaluation as anti-tumour agents against selected cancers. Bortezomib is one such inhibitor that targets the 26S proteasome, and in combination with other chemotherapeutic agents has been shown to have therapeutic potential. In contrast to the long-term control, there are several mechanisms by which the activity of an enzyme can be altered almost instantaneously:

A. Reversible inhibition by small molecules (drugs)

B. Product inhibition

C. Allosteric regulation

D. Reversible covalent modification

Which of the above mechanism follow the process of negative-feedback control and ADP-ribosylation respectively?

#Unit 4. Cell Communication and Cell Signaling
  1. A and B

  2. B and C

  3. A and C

  4. B and D

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TLS Online TPP Program

#Question id: 15834

#Unit 8. Inheritance Biology

You are interested in a new type of autosomal dominant mutation that gives purple eyes in Drosophila. You have a true-breeding purple-eyed line carrying a mutation that you call pr-1. You have isolated a second purple-eyed mutation that you call pr-2, which you have established in a true-breeding line that also carries a recessive marker st, which gives stubby legs. You cross a fly from the pr-1 line to a fly from the st, pr-2 line producing F1 females which you then cross to males from a true breeding st line (normal eyes). From this cross, 1000 progeny flies can be categorized into four different phenotypic classes:
                             
Normally, 3-factor crosses give eight different phenotypic classes, why does this particular cross give only four?

TLS Online TPP Program

#Question id: 3552

#Unit 8. Inheritance Biology

In corn, three dominant alleles, called A, C, and R, must be present to produce colored seeds. Which of the following genotype would produce 25 % color seeded plant, When cross with Aaccrr?

TLS Online TPP Program

#Question id: 10710

#Unit 10. Ecological Principles

Researcher study the diversity of 3 communities, 4 species was recorded from all community. Presence (+) and absence (-) of species are given 


What is similarity coefficient between A & B, B & C, and A & C RESPECTIVELY?

TLS Online TPP Program

#Question id: 19073

#Unit 6. System Physiology – Plant

Bacteria releases toxin or effectors, which triggered immune response in the host plant, known as__

TLS Online TPP Program

#Question id: 27036

#Unit 10. Ecological Principles

Mafia hypothesis based on
a) Taking food by theft
b) destroying all eggs of their host’s nests
c) Changing color of host making more susceptible to being eaten