TLS Online TPP Program

#Question id: 1517


Following statements are regarding to cell death and its regulation.

A. In mammals, apoptosis can be triggered by oligomerization of Bax or Bak proteins in the outer mitochondrial membrane, leading to efflux of cytochrome c and SMAC/DIABLO proteins into the cytosol; these proteins then promote caspase activation and cell death.

B. Direct interactions between pro-apoptotic and anti-apoptotic proteins lead to cell death in the absence of trophic factors.

C. Direct interactions between pro-apoptotic and anti-apoptotic proteins lead to cell death in the presence of trophic factors.

D. Once activated, apoptotic proteases called caspases cleave specific intracellular substrates, leading to the demise of a cell.

Which of the following statements are correct?

#Unit 4. Cell Communication and Cell Signaling
  1. A and B

  2. B and C

  3. C and D

  4. A, B and D