Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.

A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.

B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.

C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.

D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.

Which of the following statements are correct?

#Question id: 11443

#Unit 10. Ecological Principles

To qualify as a Biodiversity Hotspot, an area must contain__:

A .At least 1,500 species of endemic vascular plants

B .At least 70 percent land covered by vascular plants

C .At least 25 threatened species of mammals

D .At least one protected area such as national park

 Choose the correct option from the codes given below:

#Question id: 11444

#Unit 10. Ecological Principles

Ecologist have proposed following explanation to lead maximize biodiversity at tropic.

A. Higher productivity in the tropics allows for more species present

 B. Old communities have greater species than younger community

 C. Natural enemies such as predators and parasite limit competition in the tropics, which allows more species to coexist

D. Very less intensity of disturbances in the tropics promote high succession diversity

#Question id: 11445

#Unit 7. System Physiology – Animal

When the mammalian brain compares the actual temperature of the body to the preferred temperature of the body, which general component is being used?

#Question id: 11446

#Unit 7. System Physiology – Animal

A physiologist is studying the homeostatic control of blood pH. What type of receptor might be responsible for detecting changes in blood pH?

#Question id: 11447

#Unit 7. System Physiology – Animal

The correct sequence of sensory processing is ________.

#Question id: 11448

#Unit 7. System Physiology – Animal

Artificial electrical stimulation of a human's capsaicin-sensitive neurons would likely produce the sensation of ________.