Tumor-suppressor genes generally encode proteins that in one way or another inhibit cell proliferation. Loss-of-function mutations in one or more of these proliferation inhibitory proteins contribute to the development of many cancers. Prominent among the classes of proteins encoded by tumor-suppressor genes are:

A. Intracellular proteins that regulate or inhibit entry into the cell cycle

B. Receptors or signal transducers for secreted hormones or developmental signals that inhibit cell proliferation

C. Checkpoint pathway proteins that arrest the cell cycle if DNA is damaged

D. Proteins that promote apoptosis

Following genes belongs to the above class-

i. p53

ii. Rb

iii.TGF- β

iv. Caspase 3 and 7

which of the following match is correct?

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#Question id: 5764

#Unit 8. Inheritance Biology

A wild-type chromosome can be represented as ABC * DEFGH, and from this a chromosomal aberration arises that can be represented AFED * CBGH. This is known as (* = centromere)

TLS Online TPP Program

#Question id: 1656

#Unit 4. Cell Communication and Cell Signaling

Which of the following statements is TRUE of IgM?

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#Question id: 23841

#Unit 2. Cellular Organization

Which step of myosin movement along the actin filament is performed in the absence of ATP?

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#Question id: 24502

#Unit 10. Ecological Principles

60 Parasitism is generally defined  as;

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#Question id: 24253

#Unit 2. Cellular Organization

Choose the correct option

a. H3 and H4 histones first form heterodimers that then come together to form a tetramer with two molecules each of H3 and H4.

b. While H2A and H2B form heterodimers in solution but not tetramers.

c. This assembly without DNA called Histone-only Intermediates

d. First the H3.H4 assemble into tetramer (HOI) then DNA wrapped over H3.H4 tetramer.