TLS Online TPP Program

#Question id: 1536


Use the following figure to answer the question. According to figure, which of the following statement is incorrect?

#Unit 4. Cell Communication and Cell Signaling
  1. Tumors as well as normal tissues are likely to consist of small number of stem cells that have self-renewal capability and multipotentiality, precursor cells that have limited proliferative potency, and differentiated cells.

  2. Cancer stem cells are thought to be transformed from tissue specific stem cells, precursor cells and/or differentiated cells by genetic/epigenetic mutations.

  3. Cancer stem cells exist in special microenvironment “niche” and seem to keep their resistance to a variety of anti-cancer treatment methods.

  4. Cancer stem cells do not need microenvironment (hypoxic) for the maintenance of stemness, tumorigenesis, and resistance to anti-cancer treatments, chemotherapy and irradiation.

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TLS Online TPP Program

#Question id: 5715

#Unit 8. Inheritance Biology

Following some abnormality is due to Gene rearrangement on chromosome. 

A, Affecting the expression of gene

B. Disrupt the function of gene

C. Reduced recombination between gene present in inverted region

D. Cross over suppressor 

Which of the following above abnormality is may be associated with inversion?

TLS Online TPP Program

#Question id: 5716

#Unit 8. Inheritance Biology

Which of the meiotic pairing possibilities in tetraploids and their consequence is correct?

A-chromosomes pair as bivalents, segregate normally producing diploid gametes.

B- Chromosomes pair as quadrivalent, segregates normally producing tetraploid gametes.

C-Chromosome pair as Trivalents form, segregation leads to nonfunctional aneuploid gametes

 D- Chromosome pair as Trivalents form, segregation leads to producing diploid gametes

TLS Online TPP Program

#Question id: 5717

#Unit 8. Inheritance Biology

Following homologous chromosome is a heterozygous for inversion

Following some statement regarding above abnormality is correct?

A. During meiosis, one chromosome twists once at the ends of the inversion to pair with the other untwisted chromosome

B. Crossing-over within the inversion loop at meiosis connects homologous centromeres in a dicentric bridge.

C. Tension eventually breaks the dicentric bridge, forming two chromosomes with terminal deletions.

D. the RF is zero among genes within the inversion region

TLS Online TPP Program

#Question id: 5718

#Unit 8. Inheritance Biology

aneuploids may arise through nondisjunction, the failure of homologous chromosomes or sister chromatids to separate in meiosis. which of following the incorrect about nondisjuction ?

TLS Online TPP Program

#Question id: 5719

#Unit 8. Inheritance Biology

Homologous chromosomes pair in prophase I as a following way, if crossingover occur between P and Q gene of homologous chromosome?

Which of the following proceeding event due to this abnormality?

A. Dicentric chromosome become breaks at anaphase I

B. Resulting one of the gamete received chromosome with deleted segment 

C. Recombinant gamete unable to produced viable progeny

D. Unable to separation of chromosome in anaphase II

TLS Online TPP Program

#Question id: 5720

#Unit 8. Inheritance Biology

Which two of the following are the CORRECT statements ?

P. Nondisjunction in the parental meiosis is not essential to produce diploid organisms

Q. Nondisjunction in the parental meiosis is essential to produce aneuploid organisms

R. Nondisjunction in the parental meiosis is essential to produce hexaploid organism

S. Nondisjunction in the parental meiosis is essential to produce tetraploid organisms