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#Question id: 1537


Transformation of mature cells may also occur due to aberrant expression of stemness genes, resulting in cell clones with a dedifferentiated phenotype and self-renewing capacity resembling stem cells. Recent experimental evidence supporting this proposal has been provided with the induction of adult somatic cells into pluripotent stem (iPS) cells through ectopic expression of four genes encoding the pluripotency factors Oct4 and Sox2, the transcription factor Klf4, and the oncoprotein c-Myc in mouse or human fibroblasts. However, along with pluripotency comes the capability of generating teratomas. On the basis of the above information which of the following outcome is most appropriate?

#Unit 4. Cell Communication and Cell Signaling
  1. This tumorigenicity could be partly explained by the enforced expression of Oct4.

  2. This tumorigenicity could be partly explained by the enforced expression of Sox2.

  3. This tumorigenicity could be partly explained by the enforced expression of Klf4.

  4. This tumorigenicity could be partly explained by the enforced expression of c-Myc.

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TLS Online TPP Program

#Question id: 4807

#Unit 8. Inheritance Biology

Three incompletely link marker gene was found. There is a marker A gene present in middle. Cross between aaBBcc X AAbbCC to produce heterozygous were allowed test cross, which of the following test cross offspring should be least frequent?

TLS Online TPP Program

#Question id: 4808

#Unit 8. Inheritance Biology

When F1 female Drosophila of the genotype AaBbCc is test crossed, ( Gene A and B located at 10 map unit in transe configuration but gene C are independently assort for both gene. Which of the following test cross progeny that is that is more frequent?

TLS Online TPP Program

#Question id: 4809

#Unit 8. Inheritance Biology

The upper most following figure above shows the locations of four genes on the genetic map of an organism; the lower figure shows the locations of the same four genes on a physical map derived from the nucleotide sequence of the DNA of that organism. The maps are not identical because

TLS Online TPP Program

#Question id: 4810

#Unit 8. Inheritance Biology

In a haploid organism, the C and D loci are 8 m.u. apart. From a cross C d X c D, which of the following proportion following progeny classes: (a) C D; (b) c d; (c) C d

TLS Online TPP Program

#Question id: 4811

#Unit 8. Inheritance Biology

Three incompletely link gene as a B-A-C order. A cross allowed between AAbbcc X aaBBCC produce f1 progeny allowed test cross. Which of the following offspring is a result of double cross over?

TLS Online TPP Program

#Question id: 4812

#Unit 8. Inheritance Biology

Two character X and Y ,both follow law of dominance due to 3:1 F2 phenotypic ratio monohybrid cross separately If carry out dihybrid selfing cross for heterozygous genotype for both character does not follow law of independence assortment in normal environmental condition due to?