TLS Online TPP Program

#Question id: 1537


Transformation of mature cells may also occur due to aberrant expression of stemness genes, resulting in cell clones with a dedifferentiated phenotype and self-renewing capacity resembling stem cells. Recent experimental evidence supporting this proposal has been provided with the induction of adult somatic cells into pluripotent stem (iPS) cells through ectopic expression of four genes encoding the pluripotency factors Oct4 and Sox2, the transcription factor Klf4, and the oncoprotein c-Myc in mouse or human fibroblasts. However, along with pluripotency comes the capability of generating teratomas. On the basis of the above information which of the following outcome is most appropriate?

#Unit 4. Cell Communication and Cell Signaling
  1. This tumorigenicity could be partly explained by the enforced expression of Oct4.

  2. This tumorigenicity could be partly explained by the enforced expression of Sox2.

  3. This tumorigenicity could be partly explained by the enforced expression of Klf4.

  4. This tumorigenicity could be partly explained by the enforced expression of c-Myc.

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TLS Online TPP Program

#Question id: 4598

#Unit 11. Evolution and Behavior

Fossils of Thrinaxodon, a species that lived during the Triassic period, have been found in both South Africa and Antarctica. Thrinaxodon had a reptile-like skeleton and laid eggs, but small depressions on the front of its skull suggest it had whiskers and, therefore, fur. Thrinaxodon may have been warm-blooded. The fossils of Thrinaxodon are consistent with the hypothesis that ________.

TLS Online TPP Program

#Question id: 4599

#Unit 11. Evolution and Behavior

Many crustaceans (for example, lobsters, shrimp, and crayfish) use their tails to swim, but crabs have reduced tails that curl under their shells and are not used in swimming. This is an example of ________.

TLS Online TPP Program

#Question id: 4600

#Unit 11. Evolution and Behavior

Scientific theories ________.

TLS Online TPP Program

#Question id: 4601

#Unit 11. Evolution and Behavior

DDT was once considered a "silver bullet" that would permanently eradicate insect pests. Instead, DDT is largely useless against many insects. Which of these would have prevented this evolution of DDT resistance in insect pests?

TLS Online TPP Program

#Question id: 4602

#Unit 11. Evolution and Behavior

If the bacterium Staphylococcus aureus experiences a cost for maintaining one or more antibiotic-resistance genes, what would happen in environments that lack antibiotics?

TLS Online TPP Program

#Question id: 4603

#Unit 11. Evolution and Behavior

Of the following anatomical structures, which is homologous to the bones in the wing of a bird?