TLS Online TPP Program

#Question id: 1591


Which of the following is not true about helper T cells?

#Unit 4. Cell Communication and Cell Signaling
  1. They function in cell-mediated and humoral responses.

  2. They recognize polysaccharide fragments presented by class II MHC molecules.

  3. They bear surface CD4 molecules.

  4. They are subject to infection by HIV.

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TLS Online TPP Program

#Question id: 15522

#Unit 4. Cell Communication and Cell Signaling

Double negative selection do not apply on which type of T-cells?

TLS Online TPP Program

#Question id: 15523

#Unit 4. Cell Communication and Cell Signaling

The appearance of ϒδ thymocytes and αβ thymocytes during mouse fetal development. Fetal animals generate
a) more αβ T-cells than ϒδ T-cells
b) the proportion of ϒδ T-cells generated drops off dramatically after birth
c) the proportion of αβ T-cells generated drops off dramatically after birth
d) more ϒδ T-cells than αβ T cells

TLS Online TPP Program

#Question id: 15524

#Unit 4. Cell Communication and Cell Signaling

The bulk of DP thymocyte death (~95%) occurs among thymocytes that fail positive selection because 

TLS Online TPP Program

#Question id: 15525

#Unit 4. Cell Communication and Cell Signaling

In the instructive model, TCR/CD4 and TCR/CD8 coengagement generates unique signals, if a thymocyte randomly generated a TCR with an affinity for MHC Class I. which thymocyte would bind with MHC class I?

TLS Online TPP Program

#Question id: 15526

#Unit 4. Cell Communication and Cell Signaling

If a thymocyte randomly generated a TCR with an affinity for MHC Class I, the TCR and CD8 would bind MHC Class I together, and generate a signal that specifically initiated a program that is 
a) silenced CD8 expression
b) silenced CD4 expression
c) induced expression of genes specific for helper T-cell lineage function
d) induced expression of genes specific for cytotoxic T-cell lineage function

TLS Online TPP Program

#Question id: 15527

#Unit 4. Cell Communication and Cell Signaling

CD4 and CD8 T cells leave the thymus and enter the circulation as resting cells in which stage of the cell cycle?