TLS Online TPP Program

#Question id: 16953


The ability of any stem cell to self-renew and differentiate depends on the structural organization and cellular function of specialized anatomic microenvironments known as stem cell niches. These sequestered regions are typically populated by a supportive network of stromal cells. Stem cell niche stromal cells express soluble and membrane-bound proteins that regulate cell survival, proliferation, differentiation, and trafficking. Which statements is true about HSCs?

#Unit 4. Cell Communication and Cell Signaling
  1. HSCs are not found in blood
  2. The organs that have microenvironments that support the differentiation of hematopoietic stem cells actually change over the course of embryonic development.
  3. Hematopoietic stem cells actually do not change over the course of embryonic development.
  4. HSCs do not take up residence in the bone marrow, which remains the primary site of hematopoiesis throughout adult life
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TLS Online TPP Program

#Question id: 11073

#Unit 7. System Physiology – Animal

The respiratory passageways have smooth muscle in their walls. Which of the following best describes the effect of acetylcholine and epinephrine on the respiratory passageways?

TLS Online TPP Program

#Question id: 11074

#Unit 7. System Physiology – Animal

A 30-year-old woman performs a valsalva maneuver about 30 min after eating lunch. Which of the following best describes the changes in pulmonary and systemic blood volumes that occur in this woman?


TLS Online TPP Program

#Question id: 11075

#Unit 7. System Physiology – Animal

A 65-year-old man with emphysema due to 34 years of cigarette smoking is admitted to hospital due to dyspnea. With further tests the mean pulmonary arterial pressure is determined to be 45 mm Hg at rest. He is hypoxic (PO2 = 49 mm Hg), hypercapnic (85 mm Hg), and slightly acidotic. The cardiovascular and oxygen changes are due to which of the following?

TLS Online TPP Program

#Question id: 11076

#Unit 7. System Physiology – Animal

Which of the following will decrease pulmonary blood flow resistance?

TLS Online TPP Program

#Question id: 11077

#Unit 7. System Physiology – Animal

A person’s normal tidal volume is 400 ml with a dead space of 100 ml. The respiratory rate is 12 breaths/min. The person is placed on ventilator for surgery and the tidal volume is 700 with a rate of 12. What is the approximate alveolar Pco2 for this person?

TLS Online TPP Program

#Question id: 11078

#Unit 7. System Physiology – Animal

A child has been eating round candies approximately 1 and 1.5 cm in diameter and inhaled one down his airway blocking his left bronchiole. Which of the following will describe the changes that occur?