TLS Online TPP Program

#Question id: 16956


Polyclonal antibodies are raised against bovine serum albumin in rabbit. Subsequently IgG in the antiserum is purified and digested with either pepsin or papain. Out of the following possibilities, which one is correct?

#Unit 4. Cell Communication and Cell Signaling
  1. Pepsin-digested antibodies cannot precipitate the antigen
  2. Papain-digested antibodies cannot precipitate the antigen
  3. Pepsin digestion will produce two Fab molecules
  4. Pepsin-digested antibodies will lose all interchain disulfide bonds