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TLS Online TPP Program

#Question id: 16958

Plasmacytoma or myeloma tumors secrete large amounts of monoclonal antibodies into the serum and tissue fluids of the patients, and these antibodies can be purified in large quantities. Which statement is true for Bence-Jones proteins?

#Unit 4. Cell Communication and Cell Signaling
  1. tumors will secrete only the light chains, or sometimes both the light chains and the whole antibodies, into the serum. The homogenous light chains secreted by these myeloma tumors are referred to as Bence-Jones proteins.
  2. α and ¥ heavy chains led to further subclassification of these heavy chains into sub-isotypes and their corresponding antibodies.
  3. tumors will secrete only the light chains, or sometimes both the light chains and the whole antibodies, into the serum. The homogenous heavy chains secreted by these myeloma tumors are referred to as Bence-Jones proteins
  4. An antigenic determinant is defined as a region of an antigen that makes cotact with the antigen-combining region on an antibody.
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TLS Online TPP Program

#Question id: 4760

#Unit 8. Inheritance Biology

you set up a cross between true breeding wild type male fruit flies and true breeding female flies with a yellow body color. you notice in the f1 generation that half the flies, specifically all the males, have yellow body color while the females are wild type (gray). which of the following explanations is the most likely?
TLS Online TPP Program

#Question id: 4761

#Unit 8. Inheritance Biology

which of the following statements about a lethal allele is not correct?
TLS Online TPP Program

#Question id: 4762

#Unit 8. Inheritance Biology

a semilethal allele is an example of which of the following extensions of mendelian genetics?
TLS Online TPP Program

#Question id: 4763

#Unit 8. Inheritance Biology

in a rare blood type referred to as the bombay phenotype, individuals are unable to attach the a or b antigens to their red blood cells. individuals that are homozygous recessive for gene "h" have the bombay phenotype and their blood type is type "o" regardless of their abo genotype. this is an example of what extension of mendelian inheritance?
TLS Online TPP Program

#Question id: 4764

#Unit 8. Inheritance Biology

Which of the following is the best example of overdominance?
TLS Online TPP Program

#Question id: 4765

#Unit 8. Inheritance Biology

The recessive mutant allele that causes cystic fibrosis is much more frequent in Caucasians population than in other world populations. Some scientists believe heterozygotes must have had a survival advantage during plagues such as cholera that occasionally swept through this population. What concept does this illustrate?