Consider a heritable autosomal disease with an incidence in the population of 1 per thousand. On average, individuals with the disease have 80% as many children as the population average. In answering the various parts of this question, assume that mating is random. What mutation rate would be required to maintain the observed incidence of the disease in the population if the disease is dominant?

TLS Online TPP Program

#Question id: 28765

#Unit 2. Cellular Organization

Which class of H+ ATPase in the lysosomal membrane, pumps H+ into the lysosome and maintaining its lumen at an acidic pH?

TLS Online TPP Program

#Question id: 28766

#Unit 2. Cellular Organization

Lysosome H+ pump are V-type ATPases and has a similar architecture with the_____

TLS Online TPP Program

#Question id: 28767

#Unit 2. Cellular Organization

Plant vacuole act as__

a) storage organelle for nutrients and waste products

b) degradative compartment

c) an economical way of decreasing cell size

d) a controller of turgor pressure

TLS Online TPP Program

#Question id: 28768

#Unit 2. Cellular Organization

Given following paths from different sources feed substances into lysosomes for digestion, find out the A, B and C?

TLS Online TPP Program

#Question id: 28769

#Unit 2. Cellular Organization

Autophagy occurs in the following sequence of steps___

a) Nucleation of autophagosome formation by ATG9

b) Digestion of the inner membrane and the luminal contents of the autophagosome.

c) Fusion of the autophagosome with lysosomes, catalyzed by SNAREs.

d) Induction by inhibition of mTOR complex 1

e) Closure of the membrane cup to form autophagosome

TLS Online TPP Program

#Question id: 28770

#Unit 2. Cellular Organization

Autophagy can be either;

I- Nonselective autophagy

II- Selective autophagy

a) Closure of the membrane cup to form autophagosome

b) a bulk portion of cytoplasm is sequestered in autophagosomes

c) used to destroy invading microbes

d) Nucleation of autophagosome formation by ATG1

Find out the correct match statements of about selective as well as nonselective autophagy?