Consider a heritable autosomal disease with an incidence in the population of 1 per thousand. On average, individuals with the disease have 80% as many children as the population average. In answering the various parts of this question, assume that mating is random. What mutation rate would be required to maintain the observed incidence of the disease in the population if the disease is dominant?

#Question id: 7266

#Unit 5. Developmental Biology

After brief examination of the evolution of the tetrapod limb, from fish fins to human hands, has hopefully illuminated the importance of Hox gene regulation during limb development. Hox genes are critical for:

#Question id: 1748

#Unit 4. Cell Communication and Cell Signaling

Which of the folllowing is a cytokine receptor that is a member of the hematopoietin receptor family?

#Question id: 5567

#Unit 5. Developmental Biology

The cortical reaction of sea urchin eggs functions directly in ________.

#Question id: 5657

#Unit 5. Developmental Biology

Following statements regarding to the molecular processes of capacitation.

A. The sperm cell membrane is altered by the removal of cholesterol by albumin proteins in the female reproductive tract.

B. Particular proteins or carbohydrates on the sperm surface are lost during capacitation.

C. The membrane potential of the sperm cell becomes more positive as potassium ions leave the sperm. This change in membrane potential may allow calcium channels to be opened and permit calcium to enter the sperm.

D. Calcium and bicarbonate ions are critical in activating cAMP production and in facilitating the membrane fusion events of the acrosome reaction.

E. As a result of cAMP formation, protein phosphorylation occurs. Once they are phosphorylated, some proteins migrate to the surface of the sperm head. One of these proteins is juno, which is critical in sperm-egg fusion.

which one of the following combinations is correct?

#Question id: 3560

#Unit 8. Inheritance Biology

During which phase of meiosis does the segregation described by Mendel primarily occur?