You are conducting genetic linkage studies of an autosomal dominant disease. You are focused on two SSR markers that may be linked to each other and to the disease. Here is a family in which some individuals are affected:

 

Calculate LOD scores for linkage at θ = 0.1 between the disease and SSR93?

#Question id: 2155

#Unit 2. Cellular Organization

Cholesterol is

a. unrelated to any plant lipids.                     

b. not found in chloroplast membranes.

c. encoded by an intron-containing gene on chromosome 23.

d. relatively abundant in the plasma membrane and endocytic membranes.

e. synthesized in the ER.

#Question id: 2156

#Unit 2. Cellular Organization

Proteins known to be involved in Golgi apparatus independent transport of lipids include

a. StAR protein.                                 

b. Neimann-Pick C1 (NPC1) protein.

c. HMG CoA reductase.                    

d. acyl:cholesterol acyl transferase (ACAT).

e. cholesterol 7α-hydroxylase.  

#Question id: 2157

#Unit 2. Cellular Organization

Which of the following is not a metabolic derivative of cholesterol?

a. dolichol                  

b. vitamin D               

c. bile acids    

d. v-SNARE molecules                     

e. NSF

#Question id: 2158

#Unit 2. Cellular Organization

Which of the following factors increase(s) the rate of simple (passive) diffusion of a solute across a phospholipid bilayer?

#Question id: 2159

#Unit 2. Cellular Organization

A channel protein

#Question id: 2160

#Unit 2. Cellular Organization

An artificial membrane composed only of phospholipids has significant permeability to