You are conducting genetic linkage studies of an autosomal dominant disease. You are focused on two SSR markers that may be linked to each other and to the disease. Here is a family in which some individuals are affected:

 

Calculate LOD scores for linkage at θ = 0.1 between SSR62 and SSR93

#Question id: 709

#Unit 1. Molecules and their Interaction Relevant to Biology

A sequence of amino acids in a certain protein is found to be -Ser-Gly-Pro-Gly-.  The sequence is most probably part of a(n):

#Question id: 7189

#Unit 5. Developmental Biology

Following statements were made regarding vulval development in C. elegans:

A. The formation of the anchor cell is mediated by lin-12, the C. elegans homologue of the Notch gene.

B. The formation of the anchor cell is mediated by lin-12, the C. elegans homologue of the Delta gene.

C. The lin-12 gene needs to function only in that cell destined to become the uterine precursor cell.

D. Presumptive Anchor cell also need lin-12.

E. Two cells originally synthesize both the signal for uterine differentiation (the LAG-2 protein, homologous to Delta) and the receptor for this molecule (the LIN-12 protein, homologous to Notch.

Which one of the following options represents a combination of correct statements?

#Question id: 3788

#Unit 3. Fundamental Processes

The spontaneous loss of amino groups from adenine in DNA results in hypoxanthine, an uncommon base, opposite thymine. What combination of proteins could repair such damage?

#Question id: 10895

#Unit 10. Ecological Principles

Members of a guild

#Question id: 34185

#Unit 3. Fundamental Processes