Expression of MHC genes is:

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#Question id: 12181

#Unit 2. Cellular Organization

Following statements are regarding to the CFTR.

A. cystic fibrosis transmembrane conductance regulator allows Cl− ions to flow out of the cell, following their concentration gradient.

B. ATP binding to CFTR’s two nucleotide-binding domains appears to close the Cl− channel, and the hydrolysis of one ATP opens it (the other ATP remains intact).

C. the CFTR channel can open only if its regulatory domain (which is unique among ABC transporters) has been phosphorylated, thus regulating the flow of ions across the membrane.

D. The maintenance of electrical neutrality requires that the Cl− ions transported by the CFTR be accompanied by positively charged ions, mainly Na+. The transported ions are osmotically accompanied by water, thus maintaining the proper level of fluidity in secretions of the airways, intestinal tract, and the ducts of the pancreas, testes, and sweat glands.

Which of the following combination is correct?

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#Question id: 24651

#Unit 2. Cellular Organization

For the SERCA pump, how many Ca2+ ions moves across the membrane during each catalytic cycle ?

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#Question id: 24652

#Unit 2. Cellular Organization

The mechanism postulated for P-type ATPases takes into account the large conformational changes and the phosphorylation dephosphorylation of the critical:

TLS Online TPP Program

#Question id: 24653

#Unit 2. Cellular Organization

Which of the following membrane protein form channel, in the form of gap junctions between cells?

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#Question id: 24654

#Unit 2. Cellular Organization

Which of the following is not an example of an ion transporter?

TLS Online TPP Program

#Question id: 24655

#Unit 2. Cellular Organization

Which of the following integral membrane protein transport chemotherapeutic drug out of the cell and prevents their accumulation within a tumor and thus blocks their therapeutic effects?