TLS Online TPP Program

#Question id: 1809


Which of the following statements is TRUE of αβ T-cells?

#Unit 4. Cell Communication and Cell Signaling
  1. αβ T-cells initially express a pre-TCR bearing an invariant pre-β chain

  2. αβ T-cells express RAG-1 and RAG-2 at the pre-T stage

  3. αβ T-cells can be CD4+CD8− but not CD4−CD8+

  4. Unlike γδ T-cells, αβ T-cells do not rely on Notch-1 signaling pathways during their development

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TLS Online TPP Program

#Question id: 1242

#Unit 4. Cell Communication and Cell Signaling

Rhodopsin, a light-sensitive GPCR whose role in vision is dependent on its phosphorylation status, is influenced in part by the protein arrestin.  Which of the following is TRUE with regard to rhodopsin and vision?

TLS Online TPP Program

#Question id: 1243

#Unit 4. Cell Communication and Cell Signaling

One form of receptor desensitization can be mediated by negative feedback involving phosphorylation of the receptor itself by a kinase activated downstream of a second messenger. The phosphorylated receptor likely:

TLS Online TPP Program

#Question id: 1244

#Unit 4. Cell Communication and Cell Signaling

Which type of experimental evidence shows that the intrinsic GTPase activity of the Gα subunit is important for terminating effector activation?

TLS Online TPP Program

#Question id: 1245

#Unit 4. Cell Communication and Cell Signaling

Many PTB-containing proteins act as docking sites for multiple proteins. If these proteins are involved in the RTK signal transduction pathway, they most likely:

TLS Online TPP Program

#Question id: 1246

#Unit 4. Cell Communication and Cell Signaling

An SH2-containing protein contains a mutation that changes its binding pocket such that tyrosine and phosphotyrosine bind with equal affinity. As a result, MEK activity:

TLS Online TPP Program

#Question id: 1247

#Unit 4. Cell Communication and Cell Signaling

Which of the following is NOT true about the role of adapter proteins in the activation of Ras by receptor tyrosine kinases?