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TLS Online TPP Program
#Question id: 41053
#Unit 12. Biochemical Engineering
Q. According to Fourier's law of heat conduction, the heat flux (𝑱𝒒) through a medium is related to the temperature gradient (𝜵𝑻). Which of the following equations correctly represents this constitutive relationship?
TLS Online TPP Program
#Question id: 41054
#Unit 12. Biochemical Engineering
Q. Consider heat flow across a biological tissue layer that behaves according to Fourier's law (𝑱𝒒=−𝒌𝜵𝑻). If the tissue undergoes a physiological change such that its thermal conductivity (𝒌) doubles, but the temperature gradient (𝜵𝑻) across the tissue is reduced to half of its original value, how will the new heat flux (𝑱𝒒′) compare to the initial heat flux (𝑱𝒒)?
TLS Online TPP Program
#Question id: 41055
#Unit 12. Biochemical Engineering
Q. In the constitutive equation for heat conduction, 𝑱𝒒=−𝒌𝜵𝑻, what is the physical significance of the negative sign?
TLS Online TPP Program
#Question id: 41071
#Unit 8. Inheritance Biology
Q. A researcher is studying a novel gene involved in eye development in Drosophila. They isolate a mutant strain where a single nucleotide insertion has occurred in the first exon of this gene. When a heterozygous fly (one mutant allele, one wild-type allele) is observed, its eyes develop completely normally. Based on the provided principles of genetic mutations, which of the following statements best characterizes this mutation?
TLS Online TPP Program
#Question id: 41072
#Unit 8. Inheritance Biology
Q.Which of the following scenarios is a dominant-negative mutation most likely to be observed?
TLS Online TPP Program
#Question id: 41073
#Unit 8. Inheritance Biology
Q. A researcher is studying a novel receptor kinase involved in cell signaling. The functionally active form of this receptor is a homodimer that forms at the cell membrane upon ligand binding. The researcher isolates a mutant allele that produces a structurally altered, kinase-dead version of the receptor. When a heterozygous cell line (carrying one normal allele and one mutant allele) is generated, signaling is almost completely abolished, mimicking a null phenotype. Biochemical analysis reveals that the mutant protein is stably expressed and still binds to the normal protein.
which of the following best explains this observation?