You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                     

Calculate LOD scores for linkage at θ= 0.02 between SSR42 and SSR43 in Family 2.

#Question id: 72

#Unit 1. Molecules and their Interaction Relevant to Biology

For the reaction catalyzed by the enzyme hexokinase: Glucose + ATP → glucose 6-phosphate + ADP the equilibrium constant, Keq, is 7.8 × 10². In living E. coli cells, [ATP] = 5 mM, [ADP] = 0.5 mM, [glucose] = 2 mM, and [glucose 6-phosphate] = 1 mM. Which of the following conclusions made on the basis of the above calculations is incorrect?

#Question id: 73

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the Variation of Reaction Spontaneity (Sign of ΔG) given in Column I with the Signs of ΔH and ΔS given in column II.

#Question id: 73

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the Variation of Reaction Spontaneity (Sign of ΔG) given in Column I with the Signs of ΔH and ΔS given in column II.

#Question id: 74

#Unit 1. Molecules and their Interaction Relevant to Biology

The enthalpy and entropy of the initial and final states of a reacting system are shown in the table. Calculate the change in free energy for the reaction when the temperature is 4°C.

#Question id: 75

#Unit 1. Molecules and their Interaction Relevant to Biology

The experimental approach taken in current biological investigations presumes that ________.

#Question id: 76

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following illustrations is not a structural isomer of an organic compound with the molecular formula C6H14? For clarity, only the carbon skeletons are shown; hydrogen atoms that would be attached to the carbons have been omitted.