TLS Online TPP Program

#Question id: 19120


Trisomy 18 is one of the most common trisomies observed in human populations. You prepare DNA samples from two unrelated infants, both with trisomy 18, and from their parents. You then type the infants and their parents for four SSRs distributed along chromosome 18:
 

                                      
In which parent did nondisjunction occur in Family 1?

#Unit 8. Inheritance Biology
  1. Mom gave to the daughter one copies of 1B, 2C, and one each of 3A, 3B, 4A, 4B.
  2. Dad gave to the daughter one each of 1B, 1C, 2B, 2C, and two copies each of 3B and 4A.
  3. Mom gave to the daughter two copies of 1B, two copies of 2C, and one each of 3A, 3B, 4A, 4B.
  4. Dad gave to the daughter two copies of 1B, 2C, 3B,  4B.
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TLS Online TPP Program

#Question id: 4949

#Unit 11. Evolution and Behavior

What probably accounts for the switch to DNA-based genetic systems during the evolution of life on Earth?

TLS Online TPP Program

#Question id: 4951

#Unit 11. Evolution and Behavior

The synthesis of new DNA requires the prior existence of oligonucleotides to serve as primers. On Earth, these primers are small RNA molecules. This latter observation is evidence in support of the hypothesized existence of

TLS Online TPP Program

#Question id: 4952

#Unit 11. Evolution and Behavior

Several scientific laboratories across the globe are involved in research concerning the origin of life on Earth. Which of these questions is currently the most problematic and would have the greatest impact on our understanding if we were able to answer it?

TLS Online TPP Program

#Question id: 4953

#Unit 11. Evolution and Behavior

Several scientific laboratories across the globe are involved in research concerning the origin of life on Earth. Which graph below, if the results were produced abiotically, would have the greatest promise for revealing important information about the origin or Earthʹs first genetic system?

TLS Online TPP Program

#Question id: 4954

#Unit 11. Evolution and Behavior

If natural selection in a particular environment favored genetic systems that permitted the production of daughter ʺcellsʺ that were genetically dissimilar from the mother ʺcells,ʺ then one should expect selection for

I. polynucleotide polymerase with low mismatch error rates.

II. polynucleotide polymerases without proofreading capability.

III. batteries of efficient polynucleotide repair enzymes.

IV. polynucleotide polymerases with proofreading capability.

V. polynucleotide polymerases with high mismatch error rates.

TLS Online TPP Program

#Question id: 4955

#Unit 11. Evolution and Behavior

If relatively small carbonaceous chondrites from space were a significant source of Earthʹs original amino acids, then which two of these would have been most important in permitting their organic materials to survive impact with Earth?

I. Carbonaceous chondrites must contain no D-amino acids.

II. Earthʹs early atmosphere must have had little free oxygen.

III. The chondrites must have arrived on Earth before 4.2 billion years ago.

IV. Earthʹs early atmosphere must have been dense enough to dramatically slow the chondrites before they impacted.

V. The chondrites must have impacted land, rather than a large body of water.