TLS Online TPP Program

#Question id: 2092


Peripheral membrane proteins

#Unit 2. Cellular Organization
  1. contain many hydrophobic amino acid residues.

  2. contain membrane spanning domains.

  3. have covalently attached lipid or fatty acid anchors.

  4. may noncovalently interact with phospholipid heads.

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TLS Online TPP Program

#Question id: 33360

#Unit 1. Molecules and their Interaction Relevant to Biology

a. HbS (sickle-cell Hb): substitutes a Val for a Glu on the surface
b. Hb Cowtown: eliminates an ion pair involved in T-state stabilization
c. Hb Memphis: substitutes one uncharged polar residue for another of similar size on the surface
d. Hb Bibba: substitutes a Pro for a Leu involved in an α helix

Which Hb variant least likely to cause pathological symptoms

TLS Online TPP Program

#Question id: 33361

#Unit 1. Molecules and their Interaction Relevant to Biology

a. Hb Cowtown: eliminates an ion pair involved in T-state stabilization
b. Hb Milwaukee: substitutes a Glu for a Val
c. Hb Providence: substitutes an Asn for a Lys that normally projects into the central cavity of the tetramer
d. Hb Philly: substitutes a Phe for a Tyr,

Which Hb variant will not bind to BPG

TLS Online TPP Program

#Question id: 33362

#Unit 1. Molecules and their Interaction Relevant to Biology

a. Hb Cowtown: eliminates an ion pair involved in T-state stabilization
b. Hb Milwaukee: substitutes a Glu for a Val
c. Hb Providence: substitutes an Asn for a Lys that normally projects into the central cavity of the tetramer
d. Hb Philly: substitutes a Phe for a Tyr

Which Hb variant will have changed pI as compared to HbA

TLS Online TPP Program

#Question id: 33363

#Unit 1. Molecules and their Interaction Relevant to Biology

An antibody binds to an antigen with a Kd of 5 X10-8 M. At what concentration of antigen will θ be 0.2

TLS Online TPP Program

#Question id: 33364

#Unit 1. Molecules and their Interaction Relevant to Biology

An antibody binds to an antigen with a Kd of 5 X10-8 M. At what concentration of antigen will θ be 0.5

TLS Online TPP Program

#Question id: 33365

#Unit 1. Molecules and their Interaction Relevant to Biology

An antibody binds to an antigen with a Kd of 5 X10-8 M. At what concentration of antigen will θ be 0.6