TLS Online TPP Program

#Question id: 2218


Human alkaline phosphatase protein is attached to the plasma membrane by a GPI anchor. In an experiment you treat cells with each of the following enzymes and find one of them inhibits the activity of the protein because it releases it into the extracellular matrix. Which specific enzyme led you to conclude that this anchor on alkaline phosphatase was both necessary and sufficient for binding the protein to the membrane where it can perform its normal activity?

#Unit 2. Cellular Organization
  1. glycosyltransferases

  2. phospholipase C

  3. flippases

  4. floppases