TLS Online TPP Program

#Question id: 2236


The partition coefficient K, the equilibrium constant for partitioning between oil and water, for butyric acid is about 10–2, and for 1,4-butanediol it is about 10–4.  You add liposomes containing only water to a solution with an initial concentration of 1 mM butyric acid and 100 mM 1,4-butanediol outside the liposomes.  What is the relative rate of diffusion of the two substances into the liposome interior?

#Unit 2. Cellular Organization
  1. Butyric acid diffuses into the liposome 100-fold faster than butanediol.

  2. The two diffuse into the liposome at equal rates.

  3. Butanediol diffuses into the liposome 100-fold faster than butanediol.

  4. Not enough information is provided to permit an answer.