TLS Online TPP Program

#Question id: 2250


Which of the following is true about cystic fibrosis?

#Unit 2. Cellular Organization
  1. The normal CFTR channel protein is a chloride uniporter, but CF patients have a mutation that makes it require ATP.

  2.  CFTR mutations result in a mutated protein, which pumps too many chloride ions out of the cell.

  3. There are no treatments for patients with CF that are specifically targeted to the CFTR receptor.

  4. Patients with the most common mutation make a CFTR protein that is not present in the membrane.

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TLS Online TPP Program

#Question id: 12951

#Unit 7. System Physiology – Animal

If the cortical collecting tubule tubular fluid inulin concentration is 40 mg/100 ml and plasma concentration of inulin is 2.0 mg/100 ml, what is the approximate percentage of the filtered water that remains in the tubule at that point?

TLS Online TPP Program

#Question id: 12952

#Unit 7. System Physiology – Animal

Which of the following changes would tend to increase Ca2+ reabsorption in the renal tubule?

TLS Online TPP Program

#Question id: 12953

#Unit 7. System Physiology – Animal

 Which of the following diuretics inhibits Na+-2Cl−-K+ co-transport in the loop of Henle as its primary action?

TLS Online TPP Program

#Question id: 12954

#Unit 7. System Physiology – Animal

A 55-year-old male patient with hypertension has had his blood pressure reasonably well controlled by administration of a thiazide diuretic. During his last visit (6 months ago) his blood pressure was 130/75 mm Hg and his serum creatinine was 1 mg/100 ml. He has been exercising regularly for the past 2 years, but recently has complained of knee pain and began taking large amounts of a nonsteroidal anti-inflammatory drug. When he arrives at your office, his blood pressure is 155/85 and his serum creatinine is now 2.5 mg/100 ml. Which of the following best explains his increased serum creatinine?

TLS Online TPP Program

#Question id: 12955

#Unit 7. System Physiology – Animal

Which of the following would tend to decrease GFR by more than 10% in a normal kidney?

TLS Online TPP Program

#Question id: 12956

#Unit 10. Ecological Principles

For  nearly 200  years, biogeographers have  noted that  the  tropics  have  more terrestrial species than  temperate regions. Which of the following is NOT a plausible explanation for this pattern?